User Benefits
Established an effective pretreatment method for food samples of animal origin.
Realized simultaneous quantitative analysis of quinolones, sulfonamides, tetracyclines, nitrazoles, macrolides, glucocorticoids, Chloramphenicols and quinoethanol metabolites.
SHIMSEN Styra HLB SPE cartridge allows users to extract a broad range of compounds using a single sorbent and generic methodology due to its hydrophilic-lipophilic balanced sorbent characteristics.
Introduction
In recent years, veterinary drugs have been widely used to prevent infection and to promote growth and development of animals. In order to ensure the safety of food of animal origin, regulatory authorities have set maximum residue limits, MHL’s, for veterinary drugs in food for various tissues and animal types. In addition, regulators prohibit the usage of pharmacologically active compounds, which are at some point considered dangerous.
To improve selectivity and sensitivity of quantitative analysis, triple quadrupole mass spectrometers are widely used for the analysis of veterinary drugs in food [1]. To improve the efficiency of sample preparation process, hydrophilic modified styrene polymer SPE sorbent was developed and used to extract a broad range of compounds from aqueous samples.
In this method, we realized a simultaneous quantitative analysis of 53 veterinary drugs in pork using Shimadzu LCMS-8050. The samples were purified by SHIMSEN Styra HLB SPE cartridge and separated by Shim-pack GIST C18 UHPLC column.