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Analysis of PFAS in Wastewater Based on ISO21675 Using Triple Quadrupole LC/MS/MS

May 11, 2026

 
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User Benefits

Based on ISO 21675, 30 PFAS can be analyzed in various water samples, including short-chain PFAS with 4 carbon atoms and long-chain PFAS with 16 and 18 carbon atoms.

Accurate measurements are possible even in low concentration spiking recovery tests using ultrapure water and wastewater.

 

Introduction

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a large group of over 10,000 chemical compounds that are mainly composed of a carbon chain and fluorine atoms. The characteristics of PFAS depend on the carbon chain length and attached functional groups, though excellent water and oil-repelling properties and heat and chemical stability of some PFAS have led to them being used in a wide range of consumer products and industrial applications. However, their exceptional stability also makes them resistant to degradation. Concerns over the persistence of PFAS in the environment and their toxicity to organisms have led to stricter regulations globally and the development of various analytical methods to determine PFAS levels.